Topical clobetasol propionate 0.025%: a therapeutic dermatologic asset

Over several decades, topical corticosteroids (TCs) have been used in the treatment of various dermatoses such as psoriasis, contact dermatitis, and eczema, among others. The TCs act by reducing inflammation irritation after application. therapeutic effect is bestowed through their diverse biologic properties anti-inflammatory, antiproliferative, vasoconstrictive, antimitotic activity, its role reduction lymphocyte reactivity, modulation Langerhans cell expression, cellular lysosomal membrane stabilization, recruitment neutrophils monocytes, mast density sensitization immunoglobulin E. Clobetasol propionate (CP) 0.025% a class I TC available cream formulation. formulation contains half concentration conventional CP (0.025%), without loss potency. lack additives penetration enhancers (propylene glycol) further prevents cutaneous microbiome alteration. This comprehensive case series covers potent efficacy safety ImpoyzTM Cream management dermatological disorders.